exofin fusion®

Introducing the
exofin fusion® Skin Closure System

An innovative three-part skin closure system, exofin fusion® relies on premium polyester mesh strips, which quickly close and seal large incisions, form an immediate microbial barrier to protect against infection-causing bacteria, and keep the site comfortably sealed until post-surgical removal. Exofin fusion® is available in two sizes, one is ideal for medium incisions up to 20cm in length, and the other for long incisions up to 40cm in length. In addition to the high-quality mesh, our product also includes mesh anchors for added protection and easy removal, and a 2-octyl cyanoacrylate monomer with average adhesive cure time of less than one minute.

In fact, exofin fusion® not only provides for faster incision closure than sutures or staples, our product also cures up to four times faster than our leading competition. Unlike our competition, exofin fusion® also comes in a pre-sterilized tray that can be placed directly into the sterile field. Studies have shown that the combination of mesh and adhesive can reduce readmission rates and post-surgical care when compared to traditional staple closure1.

Featuring a 2-octyl monomer adhesive with a purity level greater than 99%

Other Key Benefits

  • Complete microbial barrier along incision line2
  • Waterproof barrier means patients can shower right away
  • Mesh anchors help to prevent mesh from rolling off skin prematurely and give clinicians easy access to ends of mesh for faster post-surgical removal
  • Stronger than leading competition2
  • More appealing cosmetically compared to sutures or staples
  • Uniform application distributes tension along the entire incision, preventing skin gaps from forming

1 Comparison of Economic and Clinical Outcomes between the DERMABOND® PRINEO® Skin Closure System and Skin Staples in Patients Undergoing Knee Replacement in Real World Clinical Practice. | 2 Data on file.

Skin Closure System

Featuring a Pre-Sterilized Tray & An Innovative Mesh Anchor System

  • 4cm X 22cm Mesh Patch(es)
  • Non-woven Mesh Anchors
  • 2-Octyl Monomer Adhesive 4ml

Directions For Use

Position the mesh so one half is on either side of the incision, ensuring that at least 1cm of mesh extends from each end of the incision.

Once the mesh is in the desired position, peel the supplied mesh anchor strips from the paper backing and place over each end of the mesh patch.

Spread the liquid topical skin adhesive smoothly and evenly over the entire length of the exposed mesh using the flexible bush applicator tip.

Please refer to the exofin fusion® Skin Closure System Instructions For Use for a complete description of Contraindications, Warnings, Precautions and Potential Adverse Reactions.

Cost Savings & Patient Benefits


Exofin fusion® may save your hospital money in two ways: by reducing the time individual patients spend in the OR, and by reducing the risk of acquiring a post-surgical site infection along the incision line.

Faster OR Procedures

It’s a simple formula. In the OR, time equals money. By providing faster closure speeds compared to traditional methods, exofin fusion® frees up operating rooms more quickly so hospitals may perform additional procedures each day. Other financial benefits include:

  • Frees up other OR staff to assist busy surgeons
  • Reduces the time the patient remains under anesthesia
  • Less costly postoperative healthcare visits for bandage changes

Lower Readmission Risk

Our product creates a more effective microbial barrier than traditional closure methods reducing the likelihood of readmission due to infection or other complications. A recent clinical study found a statistically significant reduction in patient readmission at 30, 60 and 90 days—a 1.8% readmission rate compared to 4.4% when using skin staples.3 Financial benefits include:

  • A lower risk of being penalized for readmission rates above the national average4
  • Reduction in total hospital stay: 12% reduction in length of hospital stay and 31% reduction in discharge to a skilled nursing facility5
  • Reduction in the use of other medical supplies such as post-surgical dressings6


Not only does exofin fusion® lower the risk of infection, our product also enhances the overall patient experience by improving patient comfort after surgery and simplifying self-care.

Simple Self-Care

When using exofin fusion® to close, patients are better suited to administer self-care after surgery:
  • Incisions closed utilizing the exofin fusion® skin closure system remain dry, keeping infection-causing bacteria and moisture away from the incision site and eliminate the need for applying and reapplying post-surgical dressings.
  • The incision site is less noticeable than sites closed with staples,improving patient confidence and self-image post-surgery.

Improved Comfort

Our superior mesh strips are strong but flexible, contouring to the body for greater patient comfort. Other comfort features include:
  • A waterproof barrier allowing patients to shower immediately after surgery. This can be especially beneficial for the new mom’s post C-section closure.
  • Mesh anchors provide for easy access point for post-surgical removal and guards against mesh from rolling up on the ends prematurely

3 A U.S. Hospital Budget Impact Analysis of a Skin Closure System Compared with Standard of Care in Hip and Knee Arthroplasty. | 4 Ibid. | 5 Ibid. | 6 Ibid.

Uses & Applications


Orthopedics for Total
Joints/Hips and Knees

The flexible mesh contours to the incision creating a positive seal over the site providing a microbial barrier against infection-causing bacteria.

Cardiovascular Closure of the Chest/Sternum

Eliminates the need for a large bulky bandage down the chest and improves patient comfort by reducing the need to do continuous dressing changes.


The flexible mesh contours to the body shape of the patient and provides continuous tension across the length of the incision unlike sutures.

for Spine

Forms an immediate barrier against infection-causing bacteria and eliminates the need to change dressings in a sensitive, hard-to-reach area.


Ideal for C-Section closure. Provides an immediate waterproof barrier and allows the new mother to shower right away.

The exofin fusion® Skin Closure Advantage

Faster cure times

Exofin fusion® adhesive cures four times faster than DERMABOND® PRINEO® in testing.7


Since our product is packaged with no fold in the mesh strip, clinicians can place the mesh flat against the wound for fast and easy application.

Safer Application

Unlike DERMABOND® PRINEO®, our product comes in a pre-sterilized, double peel pack which allows the entire container to be aseptically transferred to sterile field without fear of rolling or loose parts.

Added Convenience

Exofin fusion®’s mesh anchors helps with the removal of the mesh post-surgically, while also providing greater security to the mesh while intact on the patient’s skin.

Stronger Seal

According to internationally accepted test protocols, exofin fusion® was found to be stronger in every category, including Wound Closure, Lap Shear, Tensile Strength, and T-Peel.7

In Vitro testing of exofin fusion® showed no growth of bacteria
commonly associated with SSI’s after 72 hours, including:

  • Gram Positive MRSA
  • Pseudomonas aeruginosa
  • Escherichia coli
  • Staphylococcus aureus
  • Staphylococcus epidermidis
  • Candida albicans
  • Aspergillus brasiliensis

7 Comparison of Economic and Clinical Outcomes between the DERMABOND® PRINEO® Skin Closure System and Skin Staples
in Patients Undergoing Knee Replacement in Real World Clinical Practice and A U.S. Hospital Budget Impact Analysis of a Skin
Closure System Compared with Standard of Care in Hip and Knee Arthroplasty.

To receive more information or to place an Exofin® order
contact your Chemence Medical Customer Support Representative at 844-633-4583 .